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Fast Food Gene Therapies


               
2021 Sep 3, 3:48am   193 views  2 comments

by Al_Sharpton_for_President   follow (6)  

What are the roles of antibodies versus a durable, high quality T-cell response in protective immunity against SARS-CoV-2?

Dr. Marc Hellerstein, a vaccine researcher and toxicologist at the University of California, Berkeley, has warned of the potentially catastrophic results of neglecting T-cells and NK cells, as the COVID vaccine manufacturers have mainly focused solely on neutralizing antibodies as the measure of efficacy.

It is particularly worrisome considering that new data from the UK and Israel is reflecting these concerns, as vaccine-induced immunity rapidly decreases during the waning phase. This is partially why the White House and CDC put heavy pressure on the FDA to approve the third booster shot, leading to the resignation of 35-year veteran Marion Gruber, director of the FDA's Office of Vaccines Research & Review.

Dr. Marc Hellerstein’s study warns that “there are significant concerns about using antibody response in coronavirus infections as a sole metric of protective immunity. Antibody response is often a poor marker of prior coronavirus infection, particularly in mild infections, and is shorter-lived than virus-reactive T-cells; strong antibody response correlates with more severe clinical disease while T-cell response is correlated with less severe disease; and antibody-dependent enhancement of pathology and clinical severity has been described. Indeed, it is unclear whether antibody production is protective or pathogenic in coronavirus infections.”… “Although most vaccine candidates are focusing on spike protein as antigen, natural infection by SARS-CoV-2 induces broad epitope coverage, cross-reactive with other betacoronviruses. It will be important to understand the relation between breadth, functionality and durability of T-cell responses and resulting protective immunity. It would be a public health and general trust-in-medicine nightmare - including a boost to anti-vaccine forces - if immune protection wears off or new disease patterns develop among the immunized.”
https://pubmed.ncbi.nlm.nih.gov/32875286/

A recently published study found that T-cells and NK cells are key to preventing infection. They are fast acting and clear the infection before it occurs. Natural infection trains them against at least 29 different epitopes. Vaccines only train them against 3 epitopes.

“We identified 3-8 epitopes for each of the 6 most prevalent human leukocyte antigen (HLA) types. These epitopes were broadly shared across patients and located in regions of the virus that are not subject to mutational variation. Notably, only 3 of the 29 shared epitopes were located in the spike protein, whereas most epitopes were located in ORF1ab or the nucleocapsid protein. We also found that CD8+ T cells generally do not cross-react with epitopes in the four seasonal coronaviruses that cause the common cold. Overall, these findings can inform development of next-generation vaccines that better recapitulate natural CD8+ T cell immunity to SARS-CoV-2.” https://pubmed.ncbi.nlm.nih.gov/32875286/


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1   mell   2021 Sep 3, 7:35am  

You can have your CD8+ T cells and your NK cells tested, among a host of other immune cells. And you can eat/drink certain foods that enhance them, such as GcMAF (which you can also inject).
2   Al_Sharpton_for_President   2021 Sep 3, 7:45am  

OTS POC for cells is a tough one, though. Antibodies are quite convenient, as are antibody-based neutralization assays, but GIGO.

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