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Medical Studies almost always Bogus, sez Researcher-Author


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2017 May 6, 7:24pm   1,815 views  3 comments

by MisdemeanorRebel   ➕follow (12)   💰tip   ignore  

That’s because many medical studies are junk. It’s an open secret in the research community, and it even has a name: “the reproducibility crisis.”

For any study to have legitimacy, it must be replicated, yet only half of medical studies celebrated in newspapers hold water under serious follow-up scrutiny — and about two-thirds of the “sexiest” cutting-edge reports, including the discovery of new genes linked to obesity or mental illness, are later “disconfirmed.”

Though erring is a key part of the scientific process, this level of failure slows scientific progress, wastes time and resources and costs taxpayers excesses of $28 billion a year, writes NPR science correspondent Richard Harris in his book “Rigor Mortis: How Sloppy Science Creates Worthless Cures, Crushes Hope, and Wastes Billions” (Basic Books).

http://nypost.com/2017/05/06/medical-studies-are-almost-always-bogus/

I liked this Gem:


Add this to the truly terrible job market for post-docs — only 21 percent land tenure track jobs — and there is a greater incentive to publish splashy counterintuitive studies, which have a higher likelihood of being wrong, writes Harris.

B-b-b-but, I thought we had a STEM shortage of crisis proportions...

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1   missing   2017 May 6, 8:48pm  

Grad students and postdocs are often treated as the slave labour of tenured faculty. The success of the latter is widely measured by the size of their research groups, while their main occupation is to keep applying for research funding and to travel the conference circuit (circus). The grant review process is subjective and depends critically on networking.

Many universities accept more grad students than they intend to graduate because they need teaching assistants to run the first year classes and labs. The numbers are reduced at the qualifying exams.

(what I wrote above applies to physics)

2   curious2   2017 May 6, 8:56pm  

curious2 says

Consider as a starting example Vytorin, widely advertised on TV; in clinical studies, "Vytorin failed to show much effect."

As is typical for drug trials that show failure, publication was delayed for years compared to trials that show "success", leaving the drugs on the market to make money, inflict side effects, and confer no benefit:

Newsweek: "Why Almost Everything You Hear About Medicine Is Wrong"

The literature imbalance can also result from the use of "rescue countries," i.e. if trials in America show a drug doesn't work, PhRMA can throw cash at doctors in dirt-poor "rescue countries" to produce "studies" showing "success":

Vanity Fair: "Deadly Medicine"

This is part of why at least 30% of American medical spending consists of waste, fraud, and abuse. I'd say those categories account for more than 50% of total medical spending.

3   Ceffer   2017 May 7, 10:03am  

If you can’t hire white coat sociopathic shills to run apocryphal studies promoting addictive drugs, foods or medicines, than freedom has no meaning.

Pretty easy formula. If you oppose it, it causes weight gain, cancer, heart disease or Alzheimer’s. If you want to sell it, it causes weight loss, prevents cancer, prevents heart disease and stops Alzheimer’s dead in its tracks.

You too can be an enterprise white coat shill or food and drug lobbyist!

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