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How the mRNA toxxines kill your cells.


               
2022 Oct 9, 5:07am   2,543 views  12 comments

by Al_Sharpton_for_President   follow (6)  

Here is a nice illustration describing how the mRNA toxxines lead to the death of healthy cells.

The mRNA containing liposome (fat nanoparticle) is taken up, non-specifically, by a cell.

The mRNA is released from the liposome inside the cell where it joins the intracellular protein manufacturing machinery (ribosome) and the spike protein is produced.

Enzymes within the cell chop up the spike protein into peptides that join with Major Histocompatibility Complex (MHC).

The intact protein can also cycle up to the surface of the cell, and in the case of the toxxine coded spike protein, as it is reported to have a transmembrane domain, remain at the surface for a while. It can be released into circulation, or, a piece of cell membrane can enfold around it (endocytosis) and the protein chopped up into peptides within the endosome, where it joins MHC.

The peptide-MHC then cycles to cell's surface.

Peptide-MHC is what the T cell receptor of T cells recognizes, and T cells are alerted to what appears to be a virally infected cell.

CD4 T cells recognize peptide-MHC class II and interact with specific B cells that are turned on to make antibodies to the peptide.

CD8 T cells (killer T cells) recognize peptide-MHC class II and kill the cell displaying it.

Antibodies kill by a few mechanisms. The tail end of the antibody, the Fc (crystallizable fragment) region, attracts Natural Killer (NK) cells whcih have Fc receptors that bind to antibody Fc. The NK cells then kill the cell that has antibody attached to it. Other cell types like macrophage (big eater) cells also have Fc receptors.

The antibody Fc region also triggers complement, a serum protein, to begin a cascading activation series of reactions, that ends with holes being poked into the cell with the antibody attached to it, killing it.

As the spike protein remains at the cell surface, the cell is targeted for destruction by antibodies directed to the spike protein. As the spike protein gets released by the cell into circulation, any cell that it binds to, for example, via the cell's ACE2 receptor, will be targeted for destruction by antibodies. If the spike protein is endoctyosed into this bystander cell, it will be digested, and the peptides displayed on the cell's surface in MHC, targeting it for destruction.

The liposomes are not targeted to any particular type of cell. They bleb into cells nonspecifically. If they were to remain localized at the site of injection, then the T cell-mediated and antibody-mediated damage might remain localized. But if the liposomes were to make their way out of the site of injection, for example, into the circulatory or lymphatic system, then cells that line blood vessels (endothelial cells) could be targeted for destruction. Or if the mRNA liposomes exited capillaries into the surrounding tissue, for example, into the brain or heart, then brain or cardiac cells would be targeted for destruction.

mRNA enclosed in liposomes is a type of transfection reagent, a research tool to study protein expression in celll lines. mRNA can also be coded to knock out protein expression, a useful application. But injecting humans with non-targeted transfection reagents is extremely risky, and while being applied as a cancer therapy, it may be worth the risk, and only in controlled clinical studies with patient consent and institutional review board authorization. But being used in healthy persons to mitigate a low-probability mortality risk is very unwise and should be a crime.

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1   Patrick   2022 Oct 9, 10:53am  

I've read that the synthetic spike protein is first of all produced for far longer than they said it would be, and all over the body. And secondly the synthetic spike protein itself lasts far longer than the "natural" spike protein produced through infection with the virus that Fauci funded in Wuhan. The spike protein produced by the mRNA death jab is not the same spike protein, but modified specifically to last longer.

So getting vaxxed is not the same as being infected. It's much more dangerous.

This danger should be clear by large scale studies showing the death rates directly comparing the vaxxed vs the unvaxxed, but I don't think anyone has the guts to do such a study yet because the criminals at Pfizer who own the whores in DC forbid it. So we have to rely on statistics and the introduction date of the death jab. But that's already pretty conclusive.



2   Al_Sharpton_for_President   2022 Oct 9, 11:24am  

I know many of the patnet readers are not immunologists, so I hope the illustration and explanation helps. After a nice greasy burrito from Juan's taco truck, I pass the hours in the shitter with a nearby Roitt's essential immunology textbook. Lots of pictures, and the pages come in handy.
3   Patrick   2022 Oct 9, 12:56pm  

I had a lot of biology because I was pre-med at one time. Actually got into medical school, but didn't go.

Also, after my dad got leukemia, I spent a lot of time reading about immunology hoping I could find something useful.
4   Al_Sharpton_for_President   2022 Oct 9, 1:25pm  

Patrick says


lso, after my dad got leukemia,

ALL, AML, CLL or other?
5   Patrick   2022 Oct 10, 4:00pm  

CLL. His brother, my uncle, also died of the same thing. Could be genetic, but they also both worked with radiation (Bechtel, Argonne National Lab). I've read it's common among pilots as well, because they get more radiation up there.

The "good" thing about it is that it's rather slow, maybe 5 years from diagnosis to death.

Basically, you make too many white blood cells, and they don't work. So you get increasingly frequent strokes and infections until one of them kills you.

It's been cured in a few people now, but that was after my dad and uncle died.
6   Rin   2022 Oct 10, 4:14pm  

First of all, any mRNA, not produced by one's own body, should not be in any cell for any extended period of time.

This is why we have restriction enzymes which chop up the mRNA from our cauliflowers, avocados, & poultry meats in our diets. Otherwise, we'd be expressing other organisms' proteins. This is how we assimilate food w/o it poisoning us.

But today, some Beavis & Buttheads at Big Pharma have determined that by-passing our primary defense against food contamination was a way to induce immunity. What a joke!
7   Al_Sharpton_for_President   2022 Oct 11, 6:19am  

Yes, CLL can be a slow progressor. Rituxumab was a breakthrough therapeutic, administered in combination with chemo as R-CHOP. It came on the scene in the early-mid 2000's. There are rituximab biosimilars now. Small molecules, like ibrutinib, also were breakthrough therapeutics.
8   RedStar   2022 Oct 11, 8:22am  

I was also pre-med back in the day, this thread gives me ptsd. OChem and racist asians helped kill that dream off.

What do you think of the NovaVax alternative? is it safer by any degree?
9   mell   2022 Oct 11, 8:33am  

Al_Sharpton_for_President says

Yes, CLL can be a slow progressor. Rituxumab was a breakthrough therapeutic, administered in combination with chemo as R-CHOP. It came on the scene in the early-mid 2000's. There are rituximab biosimilars now. Small molecules, like ibrutinib, also were breakthrough therapeutics.

Definitely breakthrough medications, agree.

RedStar says

I was also pre-med back in the day, this thread gives me ptsd. OChem and racist asians helped kill that dream off.

What do you think of the NovaVax alternative? is it safer by any degree?


Novavax is definitely massively safer than the mrna shit, but it contains the s protein and definitely has short term negative impact, mid-to-long-term remains to be seen, but the data so far is looking good, much better than the mrna shit. That being said, I would recommend against any jabs since covid is mostly a mild illness and the risk benefit even with novavax is most likely not favorable for the average not-at-risk person.
10   Al_Sharpton_for_President   2022 Oct 11, 9:57am  

Spike protein multimers on a nanoparticle core. The spike protein is toxic. If the Novavax formulation stays put, that would better than if it becomes a source of soluble spike proteins lookng for cells with ACE 2 receptors to bind to.

"ACE2 expression was mainly observed in enterocytes, renal tubules, gallbladder, cardiomyocytes, male reproductive cells, placental trophoblasts, ductal cells, eye, and vasculature."

https://pubmed.ncbi.nlm.nih.gov/32715618/



11   Rin   2022 Oct 11, 3:34pm  

Al_Sharpton_for_President says


If the Novavax formulation stays put, that would better than if it becomes a source of soluble spike proteins lookng for cells with ACE 2 receptors to bind to.


Here's the thing, since the Novavax is completely formulated, the body recognizes it as an invasive structure, as oppose to 'food stuff' which is the case with the mRNA vaccines.

With the above in mind, by taking 3000 mg of Quercetin Phytosome per day for let's say a week or up to a month, those N-Vax ligands will have a tough time finding sites to hang on to as Que will be providing a stoichiometric inhibition on numerous binding sites, allowing the body's natural trash removal system to remove the N-Vax garbage out of the body.
12   RedStar   2022 Oct 11, 6:11pm  

Thanks guys. Its just that I see the noose tightening in my industry (healthcare) in terms of remaining pure blood and was thinking of the Novavax as a possibility, albeit a still far off one.

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